U.S. Route 221, US-29 to SC-56
Location: Church St and Henry St, Spartanburg Two blocks later, SC-56 splits to continue south to Union. Stay on 221 for Columbia and I-26. S to SC-295, N to SC-296 S to SC-295, N to SC-296 S to SC-295, N to US-29 S to SC-296, N to US-176/SC-9
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